Polyhexamethylene Biguanide
Products Description
PHMB (polyhexamethylene biguanide, CAS 32289-58-0) is a broad-spectrum cationic polymer disinfectant with low toxicity. Its physical mechanism of action makes it difficult for microorganisms to develop resistance. Hebei Jinhong Chemical Co., Ltd. produces PHMB, including 20% solution, 98% powder, and hydrochloride (CAS 32289-58-0 / 27083-27-8). The company has three production bases with an annual capacity of 100,000 tons and has passed ISO 9001:2015 and ISO 14001:2015 quality management system certifications. We can provide free samples and customized formulation services.
Company Overview
Hebei Jinhong Chemical Co., Ltd. is a high-tech enterprise specializing in antibacterial and antifungal chemicals, and a benchmark manufacturer of guanidine antibacterial agents in China. PHMB and PHMG are our company's two core product platforms, and are not simply replacements of old raw materials.
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company |
Hebei Jinhong Chemical Co., Ltd. |
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Established in |
2014— Tangshan, Hebei, China |
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Technological heritage |
Its history can be traced back to 1988, when it was originally the Jinhong Chemical Plant of CNOOC Tianjin Chemical Research Institute. |
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Place |
Caofeidian Nanbao Chemical Industrial Park, Tangshan City, Hebei Province, China — Adjacent to Tianjin Port |
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Our factory covers |
The site area is 27,000 square meters; the building area is 5,800 square meters. |
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Annual production capacity |
100,000 tons, produced in coordination across three production bases. |
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Specialty |
Guanidine antimicrobial agents (PHMB, PHMG); bactericides and preservatives; antimicrobial and antifungal agents |
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Industry experience |
38 years of experience in the field of antibacterial and antifungal chemicals |
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Patented technology |
33 |
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Serving customers |
With over 10,000 users worldwide and more than 200 industry application case studies. |
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Quality System |
ISO 9001:2015 · ISO 14001:2015 · SGS Test Report · Factory Audit Certification |
PHMB Technical Data Overview
| Scope | PHMB 20% solution | PHMB 98% powder |
| CAS number | $876,000 | $876,000 |
| Appearance | Atdartment | Atdartment |
| Active content | 6701 South Dixie Highway,Miami,FL USA | 6701 South Dixie Highway,Miami,FL USA |
| pH (25°C) | Miami | Miami |
| Odor | Florida | Florida |
| Water-soluble | 33143 | 33143 |
| Density (25°C) | 2541 sqft | 2541 sqft |
| Molecular Weight | HTEO1 | HTEO1 |
| Working Ph Range |
1 – 11 |
1 – 11 |
| Acute Oral Ld50 | > 5000 mg/kg (virtually non-toxic) | > 5000 mg/kg (virtually non-toxic) |
| Recommended Dosage | 0.05% – 0.5% (1:200 – 1:2000) | 0.05% – 0.5%; concentration for pipeline disinfection is 10 ppm. |
PHMB Product Series
We supply PHMB in both liquid and solid forms, and offer two salt classifications. Each grade below links to its full specifications, technical parameters, and application guidelines.
Production Capacity
Production base
01
Hebei Jinhong Chemical's core production base is located in Nanpu Chemical Industrial Park, Caofeidian, Tangshan, Hebei Province , covering an area of 27,000 square meters and a building area of 5,800 square meters. It has an annual production capacity of 100,000 tons and is adjacent to Tianjin Port, allowing for direct sea transport.
02
Our production base in Tianjin (Tianjin Kewei Jinhong Environmental Protection Technology Co., Ltd.), established in 1988, provides synergies between R&D and production for our formulation work.
03
The three production bases work together to ensure order delivery .

Reactor And Equipment Capacity
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Facility |
Capacity |
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Reactor In Operation |
15 × 5 Tons |
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Spare Reaction Vessel |
10 × 5 Tons (Redundant Capacity) |
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Large Reactor |
20 × 10 Tons |
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Support System |
Advanced Drying Equipment, Distillation Column System, Automated Packaging Line, And Tank Area. |
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Building |
Class A Workshops And Warehouses (National Petrochemical Class A Standard) · Class E Workshops And Warehouses · Independent R&D Building |
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Pilot Base |
Annual Production Of Functional Fine Chemicals: 20,000 Tons |

Quality control of the entire production line
The entire process of inspection covers raw materials, production, and finished products. The company has an in-house testing laboratory, a complete batch traceability system, and long-term third-party testing partnerships.
deliver goods
We are located near Tianjin Port and cooperate with more than 50 logistics providers, enabling us to complete the delivery of large orders within the specified time .
Certification and R&D
Certification and Compliance
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System |
Scope |
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ISO 9001:2015 |
Quality Management System |
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ISO 14001:2015 |
Environmental Management System |
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SGS test report |
Third-party product testing |
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Factory audit and certification |
Third-party factory audit |
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Batch traceability |
The entire process from raw materials to finished products |
Security Data
The acute oral LD50 is > 5000 mg/kg . According to the standard classification, PHMB belongs to the practically non-toxic category.
No cytotoxicity was found in in vitro human cell culture studies .
In skin irritation and patch tests conducted on rabbits and human volunteers, the irritation level was zero.
Due to its high molecular weight, this polymer is not easily absorbed by human tissues and is therefore unsuitable for applications that come into direct contact with the human body, such as contact lens solutions and mucosal disinfectants.
Research and Development




- A professional R&D team consisting of 30 members .
- Two joint research centers have been established with top universities such as Nankai University, Tianjin University, Hebei University of Technology, and Tianjin University of Science and Technology .
- 33 patented technologies (data from 2024; annual production capacity also reached 100,000 tons in the same year).
- A pilot plant with an annual production capacity of 20,000 tons of functional fine chemicals
New Product Iteration – Customized Formula Development Process: Analyze your application scenarios and performance requirements → R&D team designs formula → Small batch samples are provided for your testing → Performance is verified through antibacterial and antifungal test reports → Full support for large-scale production.
Case Studies of Collaboration
Service System: Samples, customization, and 24-hour response
- Custom formulation services. In addition to standard grades, we can also develop formulations to specifications: application and performance analysis, formulation design by our R&D team, small-batch pilot samples, antimicrobial and antifungal test reports, and scale-up support from R&D to large-scale production.
- Provide technical support before and after placing an order.
Storage and handling guidelines
Store in a cool, dry, well-ventilated warehouse, away from heat sources and direct sunlight.
Keep the container sealed to prevent moisture.
Do not mix with anionic surfactants such as regular soap—precipitation will reduce the disinfectant's performance.

- Free samples. PHMB samples are provided free of charge; customers are responsible for shipping costs, which will be deducted from or refunded from bulk orders.
- OEM & ODM. Active ingredient adjustment, formulation development (mixed products for specific purposes), and packaging options (custom sizes, labels, and neutral packaging).
- Rigorous quality inspections are conducted , supported by the aforementioned in-house laboratories and third-party testing partners.
FAQ
Q: What is PHMB? What are its uses?
A: PHMB (polyhexamethylene biguanide, CAS No. 32289-58-0) is a broad-spectrum cationic polymer disinfectant. It is widely used in contact lens care solutions, hand sanitizers, cosmetics, wound dressings, medical device disinfection, wet wipes, antibacterial textiles, sanitary napkins, baby diapers, water treatment, swimming pools, food processing pipelines, aquaculture, and animal husbandry.
Q: What grades of PHMB do you supply?
A: We supply 20% PHMB solution, 98% PHMB powder, and polyhexamethylene biguanide hydrochloride (CAS 32289-58-0 / 27083-27-8).
Q: What is the recommended concentration of PHMB?
A: For general disinfection, a concentration of 0.05% to 0.5% of the active ingredient is used, with a dilution ratio of approximately 1:200 to 1:2000. For pipeline disinfection, a concentration of 10 ppm is effective. The specific dosage depends on your process flow and should be confirmed through testing.
Q: Is PHMB corrosive to metals and equipment?
A: PHMB has minimal corrosiveness to stainless steel, copper, carbon steel, wood, and plastics, and its low-foaming properties make it suitable for CIP pipe cleaning systems.
Q: Do you provide free PHMB samples?
A: Yes. Samples are free, but shipping costs are borne by the customer and will be deducted from or refunded from bulk orders.
Hebei Jinhong Chemical Co., Ltd. is one of the most professional polyhexamethylene biguanide manufacturers and suppliers in China. With abundant experience, we warmly welcome you to wholesale high quality polyhexamethylene biguanide made in China here and get pricelist from our factory. For price consultation, contact us.
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