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Product Profile
This high-molecular-weight polymeric agent is poorly absorbed by biological tissues, making it safe for regular human contact. Rinsing residues off surfaces is straightforward due to its low-foaming nature. Laboratory evaluations have shown no signs of cytotoxicity in human cell cultures, and skin patch tests performed on both rabbits and human volunteers confirmed zero irritation potential.
Technical Specifications
|
Parameter |
Value |
|
Appearance |
Colorless or pale yellow transparent liquid |
|
Active substance content |
≥ 20% |
|
pH (at 25°C) |
4.0 – 6.5 |
|
Odor |
None |
|
Solubility in water |
Fully miscible |
Performance Highlights
Polyhexamethylene Biguanide Hydrochloride operates through a physical mode of action: positively charged polymer chains electrostatically bind to negatively charged microbial cell surfaces, leading to membrane rupture, disruption of energy metabolism, and eventual cell death. This physical mechanism effectively avoids the development of drug-resistant strains. Additionally, the product generates very little foam, simplifying rinse steps.
Storage and Handling Guidelines
Store the product in a tightly sealed container placed in a cool, dry, and properly ventilated area. Avoid prolonged exposure to heat sources or direct sunlight to preserve product integrity and prevent moisture uptake.
Frequently Asked Questions (FAQ)
Q: What working concentration is typically used?
A final concentration of 0.05% to 0.5% is commonly applied, achieved by diluting the 20% solution 200- to 2000-fold. However, optimization through on-site testing is recommended for each specific process.
Q: Is this product compatible with soaps and other detergents?
Mixing with anionic surfactants (frequently found in common soaps) should be avoided, as it may cause precipitation and reduce disinfectant performance.
Q: Is there any toxicity concern for humans?
The acute oral LD50 exceeds 5000 mg/kg, placing Polyhexamethylene Biguanide Hydrochloride in the "practically non-toxic" category under standard classification systems.
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